Intramuscular progesterone optimizes live birth from programmed frozen embryo transfer: a randomized clinical trial
To determine whether vaginal progesterone for programmed endometrial preparation is noninferior to intramuscular progesterone in terms of live birth rates from frozen embryo transfer (FET). Three-armed, randomized, controlled noninferiority trial. Multicenter fertility clinic. A total of 1,346 volunteer subjects planning vitrified-warmed transfer of high-quality nonbiopsied blastocysts were screened, of whom 1,125 subjects were ultimately enrolled and randomly assigned to treatment.
https://www.focusonreproduction.eu/article/News-in-Reproduction-Frozen-embryo-transfer
https://academic.oup.com/humrep/article/36/5/1260/6208126?login=true
Is diminished ovarian reserve a risk factor for miscarriage? Results of a systematic review and meta-analysis
AbstractBACKGROUND. Anti-Müllerian hormone (AMH) serum concentration and antral follicle count (AFC), as measured by transvaginal ultrasonography, accurately re
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SARS-CoV-2 spike protein seropositivity from vaccination or infection does not cause sterility
Several reports claim that the purported similarity between syncytin-1 and the SARS-CoV-2 spike protein may induce immune cross-reactivity resulting in female sterility. We used frozen embryo transfer as a model for comparing the implantation rates between SARS-CoV-2 vaccine seropositive, infection seropositive, and seronegative women.
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Delay in IVF treatment up to 180 days does not affect pregnancy outcomes in women with diminished ovarian reserve
A novel coronavirus (SARS-CoV-2) that can infect humans and cause severe respiratory tract illness was first identified in Wuhan, China in December of 2019 ( Zhu et al., 2020). Since this virus emerged, it has spread throughout the world, with the first case in the USA reported on 19 January 2020 ( Holshue et al., 2020).
Risk of breast cancer in women treated with ovarian stimulation drugs for infertility: a systematic review and meta-analysis
To evaluate the evidence addressing the association between the use of ovarian stimulation drugs and the risk of breast cancer. Systematic review and meta-analysis. Women without any previous history of breast cancer undergoing ovarian stimulation. Electronic databases were searched from 1990 until January 2020.
Endometriosis research from ESHRE
In support of Endometriosis Awareness Month – March 2021 – we have collated a selection of recent articles published in the ESHRE journals. The featured articles hold great relevance for both clinicians and scientists and are published Open Access, or are freely available for you to read until 30th June.